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SMILES: C[C@@H]1CN(CCN1C(=O)Cn1nc(C)cc1C)c1sc(nc1-c1nc2ccccc2[nH]1)C(F)(F)F

InChI Key: InChIKey=WJEJRGIYUYURNR-OAHLLOKOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208725   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15


(Homo sapiens (Human))		BDBM208725
PNG
(US9266876, 192)
Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1nc(C)cc1C)c1sc(nc1-c1nc2ccccc2[nH]1)C(F)(F)F
Show InChI InChI=1S/C23H24F3N7OS/c1-13-10-14(2)33(30-13)12-18(34)32-9-8-31(11-15(32)3)21-19(29-22(35-21)23(24,25)26)20-27-16-6-4-5-7-17(16)28-20/h4-7,10,15H,8-9,11-12H2,1-3H3,(H,27,28)/t15-/m1/s1
UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/a7.437



Actelion Pharmaceuticals Ltd.

US Patent


Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...

US Patent US9266876 (2016)


BindingDB Entry DOI: 10.7270/Q2DB80NB
More data for this
Ligand-Target Pair