BDBM208963 US9266881, 10-4

SMILES: O=c1n(CCc2ccc3ncccc3n2)nc2c(cccn12)-c1ccncc1

InChI Key: InChIKey=VRUXRYNFEDNSPK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM208963 (US9266881, 10-4) Show SMILES O=c1n(CCc2ccc3ncccc3n2)nc2c(cccn12)-c1ccncc1 Show InChI InChI=1S/C21H16N6O/c28-21-26-13-2-3-17(15-7-11-22-12-8-15)20(26)25-27(21)14-9-16-5-6-18-19(24-16)4-1-10-23-18/h1-8,10-13H,9,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	103	-9.53	n/a	n/a	n/a	n/a	n/a	7.2	25
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunn...				US Patent US9266881 (2016) BindingDB Entry DOI: 10.7270/Q2154FVR
					More data for this Ligand-Target Pair