null

SMILES: NC(=N)NCCC[C@@H]1NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O

InChI Key: InChIKey=GBLMEOUQOPSPSY-ARESNPRRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-degrading enzyme (Homo sapiens (Human))	BDBM209024 (US9243038, 2a (cis olefin) | US9243038, 2b (trans ...) Show SMILES NC(=N)NCCC[C@@H]1NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O |r,t:11| Show InChI InChI=1S/C41H55N9O7/c42-37(54)30-14-7-8-22-45-38(55)32(25-27-16-18-29(19-17-27)36(53)28-12-5-2-6-13-28)49-40(57)33(24-26-10-3-1-4-11-26)50-39(56)31(15-9-23-46-41(43)44)48-35(52)21-20-34(51)47-30/h2,5-6,12-13,16-21,26,30-33H,1,3-4,7-11,14-15,22-25H2,(H2,42,54)(H,45,55)(H,47,51)(H,48,52)(H,49,57)(H,50,56)(H4,43,44,46)/b21-20+/t30-,31-,32+,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair
Insulin-degrading enzyme (Homo sapiens (Human))	BDBM209024 (US9243038, 2a (cis olefin) | US9243038, 2b (trans ...) Show SMILES NC(=N)NCCC[C@@H]1NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O |r,t:11| Show InChI InChI=1S/C41H55N9O7/c42-37(54)30-14-7-8-22-45-38(55)32(25-27-16-18-29(19-17-27)36(53)28-12-5-2-6-13-28)49-40(57)33(24-26-10-3-1-4-11-26)50-39(56)31(15-9-23-46-41(43)44)48-35(52)21-20-34(51)47-30/h2,5-6,12-13,16-21,26,30-33H,1,3-4,7-11,14-15,22-25H2,(H2,42,54)(H,45,55)(H,47,51)(H,48,52)(H,49,57)(H,50,56)(H4,43,44,46)/b21-20+/t30-,31-,32+,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair