BDBM209037 US9243038, 10

SMILES: CCCCC1NC(=O)[C@H](CCC(N)=O)NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC1=O)C(N)=O

InChI Key: InChIKey=DCXHBDBBXCZUFL-WFQYMVRASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human))	BDBM209037 (US9243038, 10) Show SMILES CCCCC1NC(=O)[C@H](CCC(N)=O)NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC1=O)C(N)=O |r,t:17| Show InChI InChI=1S/C37H47N7O8/c1-2-3-11-27-36(51)44-29(22-23-13-15-25(16-14-23)33(48)24-9-5-4-6-10-24)35(50)40-21-8-7-12-26(34(39)49)41-31(46)19-20-32(47)42-28(37(52)43-27)17-18-30(38)45/h4-6,9-10,13-16,19-20,26-29H,2-3,7-8,11-12,17-18,21-22H2,1H3,(H2,38,45)(H2,39,49)(H,40,50)(H,41,46)(H,42,47)(H,43,52)(H,44,51)/b20-19+/t26-,27?,28-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair