BDBM209038 US9243038, 11

SMILES: CC(C)CC1NC(=O)[C@H](CCC(N)=O)NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC1=O)C(N)=O

InChI Key: InChIKey=XTMKJCDTSRCWOT-IUAYXUFUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human))	BDBM209038 (US9243038, 11) Show SMILES CC(C)CC1NC(=O)[C@H](CCC(N)=O)NC(=O)\C=C\C(=O)N[C@@H](CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC1=O)C(N)=O |r,t:17| Show InChI InChI=1S/C37H47N7O8/c1-22(2)20-28-37(52)44-29(21-23-11-13-25(14-12-23)33(48)24-8-4-3-5-9-24)35(50)40-19-7-6-10-26(34(39)49)41-31(46)17-18-32(47)42-27(36(51)43-28)15-16-30(38)45/h3-5,8-9,11-14,17-18,22,26-29H,6-7,10,15-16,19-21H2,1-2H3,(H2,38,45)(H2,39,49)(H,40,50)(H,41,46)(H,42,47)(H,43,51)(H,44,52)/b18-17+/t26-,27-,28?,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair