BDBM209040 US9243038, 14

SMILES: C[C@H]1NC(=O)\C=C\C(=O)NC(CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O

InChI Key: InChIKey=UEBMZFSNWFUJCZ-SPZZYLIGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human))	BDBM209040 (US9243038, 14) Show SMILES C[C@H]1NC(=O)\C=C\C(=O)NC(CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O |r,t:5| Show InChI InChI=1S/C38H48N6O7/c1-24-36(49)43-31(22-25-10-4-2-5-11-25)38(51)44-30(23-26-15-17-28(18-16-26)34(47)27-12-6-3-7-13-27)37(50)40-21-9-8-14-29(35(39)48)42-33(46)20-19-32(45)41-24/h3,6-7,12-13,15-20,24-25,29-31H,2,4-5,8-11,14,21-23H2,1H3,(H2,39,48)(H,40,50)(H,41,45)(H,42,46)(H,43,49)(H,44,51)/b20-19+/t24-,29?,30-,31+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair