null

SMILES: OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(Cl)c2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1

InChI Key: InChIKey=QHUOKCSYRBRCEQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209063 (US9266877, 9) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(Cl)c2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C33H25ClN6O3S/c34-23-7-3-5-20(15-23)17-40-18-22(16-35-40)24-11-12-29(37-30(24)32(42)43)39-14-13-21-6-4-8-25(26(21)19-39)31(41)38-33-36-27-9-1-2-10-28(27)44-33/h1-12,15-16,18H,13-14,17,19H2,(H,42,43)(H,36,38,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	-11.2	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209063 (US9266877, 9) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(Cl)c2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C33H25ClN6O3S/c34-23-7-3-5-20(15-23)17-40-18-22(16-35-40)24-11-12-29(37-30(24)32(42)43)39-14-13-21-6-4-8-25(26(21)19-39)31(41)38-33-36-27-9-1-2-10-28(27)44-33/h1-12,15-16,18H,13-14,17,19H2,(H,42,43)(H,36,38,41)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	378	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair