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SMILES: Cc1cccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)c1

InChI Key: InChIKey=WIPYJTKJNLKGHM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209067 (US9266877, 13) Show SMILES Cc1cccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)c1 Show InChI InChI=1S/C34H28N6O3S/c1-21-6-4-7-22(16-21)18-40-19-24(17-35-40)25-12-13-30(37-31(25)33(42)43)39-15-14-23-8-5-9-26(27(23)20-39)32(41)38-34-36-28-10-2-3-11-29(28)44-34/h2-13,16-17,19H,14-15,18,20H2,1H3,(H,42,43)(H,36,38,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12	-10.8	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209067 (US9266877, 13) Show SMILES Cc1cccc(Cn2cc(cn2)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)c1 Show InChI InChI=1S/C34H28N6O3S/c1-21-6-4-7-22(16-21)18-40-19-24(17-35-40)25-12-13-30(37-31(25)33(42)43)39-15-14-23-8-5-9-26(27(23)20-39)32(41)38-34-36-28-10-2-3-11-29(28)44-34/h2-13,16-17,19H,14-15,18,20H2,1H3,(H,42,43)(H,36,38,41)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	498	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair