null

SMILES: OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(n2)N2CCCC2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1

InChI Key: InChIKey=LTEDVMOGBGJUTC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209076 (US9266877, 22) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(n2)N2CCCC2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C36H32N8O3S/c45-34(41-36-39-29-10-1-2-11-30(29)48-36)27-9-5-7-23-15-18-43(22-28(23)27)32-14-13-26(33(40-32)35(46)47)24-19-37-44(20-24)21-25-8-6-12-31(38-25)42-16-3-4-17-42/h1-2,5-14,19-20H,3-4,15-18,21-22H2,(H,46,47)(H,39,41,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	-11.2	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209076 (US9266877, 22) Show SMILES OC(=O)c1nc(ccc1-c1cnn(Cc2cccc(n2)N2CCCC2)c1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C36H32N8O3S/c45-34(41-36-39-29-10-1-2-11-30(29)48-36)27-9-5-7-23-15-18-43(22-28(23)27)32-14-13-26(33(40-32)35(46)47)24-19-37-44(20-24)21-25-8-6-12-31(38-25)42-16-3-4-17-42/h1-2,5-14,19-20H,3-4,15-18,21-22H2,(H,46,47)(H,39,41,45)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	214	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair