null

SMILES: OC(=O)c1nc(ccc1-c1cnn(c1)C1CCc2ccccc12)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1

InChI Key: InChIKey=PDMPXJMUNXTDJX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209091 (US9266877, 37) Show SMILES OC(=O)c1nc(ccc1-c1cnn(c1)C1CCc2ccccc12)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C35H28N6O3S/c42-33(39-35-37-28-10-3-4-11-30(28)45-35)26-9-5-7-22-16-17-40(20-27(22)26)31-15-13-25(32(38-31)34(43)44)23-18-36-41(19-23)29-14-12-21-6-1-2-8-24(21)29/h1-11,13,15,18-19,29H,12,14,16-17,20H2,(H,43,44)(H,37,39,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	17	-10.6	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209091 (US9266877, 37) Show SMILES OC(=O)c1nc(ccc1-c1cnn(c1)C1CCc2ccccc12)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C35H28N6O3S/c42-33(39-35-37-28-10-3-4-11-30(28)45-35)26-9-5-7-22-16-17-40(20-27(22)26)31-15-13-25(32(38-31)34(43)44)23-18-36-41(19-23)29-14-12-21-6-1-2-8-24(21)29/h1-11,13,15,18-19,29H,12,14,16-17,20H2,(H,43,44)(H,37,39,42)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	347	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair