null

SMILES: CN(C)CCCOc1ccccc1Cn1cc(cn1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1

InChI Key: InChIKey=CAPFUCBHTFYKQQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM209101 (US9266877, 47) Show SMILES CN(C)CCCOc1ccccc1Cn1cc(cn1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C38H37N7O4S/c1-43(2)18-8-20-49-32-13-5-3-9-26(32)22-45-23-27(21-39-45)28-15-16-34(41-35(28)37(47)48)44-19-17-25-10-7-11-29(30(25)24-44)36(46)42-38-40-31-12-4-6-14-33(31)50-38/h3-7,9-16,21,23H,8,17-20,22,24H2,1-2H3,(H,47,48)(H,40,42,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	16	-10.6	n/a	n/a	n/a	n/a	n/a	n/a	25
ABBVIE INC. US Patent					Assay Description The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Mus musculus (Mouse))	BDBM209101 (US9266877, 47) Show SMILES CN(C)CCCOc1ccccc1Cn1cc(cn1)-c1ccc(nc1C(O)=O)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1 Show InChI InChI=1S/C38H37N7O4S/c1-43(2)18-8-20-49-32-13-5-3-9-26(32)22-45-23-27(21-39-45)28-15-16-34(41-35(28)37(47)48)44-19-17-25-10-7-11-29(30(25)24-44)36(46)42-38-40-31-12-4-6-14-33(31)50-38/h3-7,9-16,21,23H,8,17-20,22,24H2,1-2H3,(H,47,48)(H,40,42,46)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	881	n/a	n/a	n/a	n/a
ABBVIE INC. US Patent					Assay Description The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...				US Patent US9266877 (2016) BindingDB Entry DOI: 10.7270/Q2H41Q7V
					More data for this Ligand-Target Pair