BDBM209329 US9266883, 87

SMILES: CN(C)CC(C)(O)CNc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc23)ncc1C#N

InChI Key: InChIKey=UMCGEVIWTWEHBE-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (FGFR4) (Homo sapiens (Human))	BDBM209329 (US9266883, 87) Show SMILES CN(C)CC(C)(O)CNc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C23H29N7O4/c1-23(34,14-29(2)3)13-26-18-8-20(25-10-17(18)9-24)28-22(33)30-6-4-5-15-7-16(11-31)19(12-32)27-21(15)30/h7-8,10,12,31,34H,4-6,11,13-14H2,1-3H3,(H2,25,26,28,33)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair