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SMILES: COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCNCC4=O)c(C=O)nc23)ncc1C#N

InChI Key: InChIKey=NODJSZDQTKGINK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209339   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 4 [388-802]


(Homo sapiens (Human))		BDBM209339
PNG
(US9266883, 110)
Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCNCC4=O)c(C=O)nc23)ncc1C#N
Show InChI InChI=1S/C24H28N8O4/c1-36-8-5-27-19-10-21(28-12-18(19)11-25)30-24(35)32-6-2-3-16-9-17(20(15-33)29-23(16)32)14-31-7-4-26-13-22(31)34/h9-10,12,15,26H,2-8,13-14H2,1H3,(H2,27,28,30,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/a7.530



Novartis AG

US Patent


Assay Description
Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...

US Patent US9266883 (2016)


BindingDB Entry DOI: 10.7270/Q2CC0ZGP
More data for this
Ligand-Target Pair