BDBM209543 US9271969, 31

SMILES: OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccccc1

InChI Key: InChIKey=ASGSXSYUIWQRLX-XUZLLXQOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM209543 (US9271969, 31) Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccccc1 |r,wD:4.3,(11.99,-5.75,;10.65,-4.98,;10.65,-3.44,;9.32,-5.75,;7.98,-4.98,;7.98,-3.44,;6.65,-2.67,;5.32,-3.44,;5.32,-4.98,;6.65,-5.75,;3.98,-2.67,;2.65,-3.44,;1.32,-2.67,;1.32,-1.13,;2.65,-.36,;3.98,-1.13,;-.02,-.36,;-.02,1.18,;-1.35,1.95,;-2.69,1.18,;-4.15,1.66,;-5.06,.41,;-4.15,-.83,;-2.69,-.36,;-1.35,-1.13,;-6.6,.41,;-7.37,-.92,;-7.37,1.75,;-8.91,1.75,;-9.68,3.08,;-8.91,4.41,;-9.68,5.75,;-11.22,5.75,;-11.99,4.41,;-11.22,3.08,)| Show InChI InChI=1S/C29H29N3O3/c33-28(34)16-20-6-8-22(9-7-20)23-10-12-24(13-11-23)25-14-15-27-31-26(19-32(27)18-25)29(35)30-17-21-4-2-1-3-5-21/h1-5,10-15,18-20,22H,6-9,16-17H2,(H,30,35)(H,33,34)/t20-,22?	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM209543 (US9271969, 31) Show SMILES OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccccc1 |r,wD:4.3,(11.99,-5.75,;10.65,-4.98,;10.65,-3.44,;9.32,-5.75,;7.98,-4.98,;7.98,-3.44,;6.65,-2.67,;5.32,-3.44,;5.32,-4.98,;6.65,-5.75,;3.98,-2.67,;2.65,-3.44,;1.32,-2.67,;1.32,-1.13,;2.65,-.36,;3.98,-1.13,;-.02,-.36,;-.02,1.18,;-1.35,1.95,;-2.69,1.18,;-4.15,1.66,;-5.06,.41,;-4.15,-.83,;-2.69,-.36,;-1.35,-1.13,;-6.6,.41,;-7.37,-.92,;-7.37,1.75,;-8.91,1.75,;-9.68,3.08,;-8.91,4.41,;-9.68,5.75,;-11.22,5.75,;-11.99,4.41,;-11.22,3.08,)| Show InChI InChI=1S/C29H29N3O3/c33-28(34)16-20-6-8-22(9-7-20)23-10-12-24(13-11-23)25-14-15-27-31-26(19-32(27)18-25)29(35)30-17-21-4-2-1-3-5-21/h1-5,10-15,18-20,22H,6-9,16-17H2,(H,30,35)(H,33,34)/t20-,22?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair