BDBM210094 US9270353, 55

SMILES: CC(C)(O)\C=C1\C[C@](C)(N=C(N)S1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F

InChI Key: InChIKey=VFKPCIBPVPIWMS-BQEXRTDESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM210094 (US9270353, 55) Show SMILES CC(C)(O)\C=C1\C[C@](C)(N=C(N)S1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F |r,t:9| Show InChI InChI=1S/C22H22FN5O2S/c1-21(2,30)9-15-10-22(3,28-20(25)31-15)16-8-14(5-6-17(16)23)27-19(29)18-7-4-13(11-24)12-26-18/h4-9,12,30H,10H2,1-3H3,(H2,25,28)(H,27,29)/b15-9-/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	5.0	n/a
Shionogi & Co., Ltd. US Patent					Assay Description 48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...				US Patent US9273053 (2016) BindingDB Entry DOI: 10.7270/Q24Q7SVG
					More data for this Ligand-Target Pair