BDBM210228 US9290451, 41

SMILES: Cc1nc(no1)C(C)(C)NC(=O)c1cccc(n1)-c1cccc(Cl)c1

InChI Key: InChIKey=KXYMJQFHXYKFSA-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM210228 (US9290451, 41) Show SMILES Cc1nc(no1)C(C)(C)NC(=O)c1cccc(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H17ClN4O2/c1-11-20-17(23-25-11)18(2,3)22-16(24)15-9-5-8-14(21-15)12-6-4-7-13(19)10-12/h4-10H,1-3H3,(H,22,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM210228 (US9290451, 41) Show SMILES Cc1nc(no1)C(C)(C)NC(=O)c1cccc(n1)-c1cccc(Cl)c1 Show InChI InChI=1S/C18H17ClN4O2/c1-11-20-17(23-25-11)18(2,3)22-16(24)15-9-5-8-14(21-15)12-6-4-7-13(19)10-12/h4-10H,1-3H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	99.9	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair