BDBM210398 US9290451, 140

SMILES: CC(C)C[C@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(n1)-c1cccc(Cl)c1)C(N)=O

InChI Key: InChIKey=QCOCMPRMHVAYGY-INIZCTEOSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM210398 (US9290451, 140) Show SMILES CC(C)C[C@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(n1)-c1cccc(Cl)c1)C(N)=O |r| Show InChI InChI=1S/C21H23ClF2N4O2/c1-12(2)8-16(19(25)29)27-20(30)15-6-7-17(28-10-21(23,24)11-28)18(26-15)13-4-3-5-14(22)9-13/h3-7,9,12,16H,8,10-11H2,1-2H3,(H2,25,29)(H,27,30)/t16-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM210398 (US9290451, 140) Show SMILES CC(C)C[C@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(n1)-c1cccc(Cl)c1)C(N)=O |r| Show InChI InChI=1S/C21H23ClF2N4O2/c1-12(2)8-16(19(25)29)27-20(30)15-6-7-17(28-10-21(23,24)11-28)18(26-15)13-4-3-5-14(22)9-13/h3-7,9,12,16H,8,10-11H2,1-2H3,(H2,25,29)(H,27,30)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	305	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair