BDBM210507 US9290451, 219

SMILES: Cc1nc(no1)C(NC(=O)c1ccc(C2CC2)c(OCC2CCOCC2)n1)C1CC1

InChI Key: InChIKey=OTSOYXPPWPAFFH-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM210507 (US9290451, 219) Show SMILES Cc1nc(no1)C(NC(=O)c1ccc(C2CC2)c(OCC2CCOCC2)n1)C1CC1 Show InChI InChI=1S/C22H28N4O4/c1-13-23-20(26-30-13)19(16-4-5-16)25-21(27)18-7-6-17(15-2-3-15)22(24-18)29-12-14-8-10-28-11-9-14/h6-7,14-16,19H,2-5,8-12H2,1H3,(H,25,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.14E+3	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM210507 (US9290451, 219) Show SMILES Cc1nc(no1)C(NC(=O)c1ccc(C2CC2)c(OCC2CCOCC2)n1)C1CC1 Show InChI InChI=1S/C22H28N4O4/c1-13-23-20(26-30-13)19(16-4-5-16)25-21(27)18-7-6-17(15-2-3-15)22(24-18)29-12-14-8-10-28-11-9-14/h6-7,14-16,19H,2-5,8-12H2,1H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10.8	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair