BDBM210699 US9290451, 348

SMILES: Cc1nc(no1)[C@H](CC1CC1)NC(=O)c1cccc(n1)-c1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=KQIHEVJPDJPBJV-SFHVURJKSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM210699 (US9290451, 348) Show SMILES Cc1nc(no1)[C@H](CC1CC1)NC(=O)c1cccc(n1)-c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H18F4N4O2/c1-11-26-19(29-31-11)18(9-12-5-6-12)28-20(30)17-4-2-3-16(27-17)13-7-8-15(22)14(10-13)21(23,24)25/h2-4,7-8,10,12,18H,5-6,9H2,1H3,(H,28,30)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	24.6	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM210699 (US9290451, 348) Show SMILES Cc1nc(no1)[C@H](CC1CC1)NC(=O)c1cccc(n1)-c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H18F4N4O2/c1-11-26-19(29-31-11)18(9-12-5-6-12)28-20(30)17-4-2-3-16(27-17)13-7-8-15(22)14(10-13)21(23,24)25/h2-4,7-8,10,12,18H,5-6,9H2,1H3,(H,28,30)/t18-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair