BDBM210914 US9273043, B155(o)

SMILES: C[C@@H](O)[C@H](O)c1cnc(N2CCN(C[C@H]2C)C(=O)Nc2nc3cc(F)ccc3s2)c(F)c1

InChI Key: InChIKey=ZATUJVIEPXVGPT-FMTVUPSXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM210914 (US9273043, B155(o)) Show SMILES C[C@@H](O)[C@H](O)c1cnc(N2CCN(C[C@H]2C)C(=O)Nc2nc3cc(F)ccc3s2)c(F)c1 |r| Show InChI InChI=1S/C21H23F2N5O3S/c1-11-10-27(21(31)26-20-25-16-8-14(22)3-4-17(16)32-20)5-6-28(11)19-15(23)7-13(9-24-19)18(30)12(2)29/h3-4,7-9,11-12,18,29-30H,5-6,10H2,1-2H3,(H,25,26,31)/t11-,12-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	7.2	37
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM210914 (US9273043, B155(o)) Show SMILES C[C@@H](O)[C@H](O)c1cnc(N2CCN(C[C@H]2C)C(=O)Nc2nc3cc(F)ccc3s2)c(F)c1 |r| Show InChI InChI=1S/C21H23F2N5O3S/c1-11-10-27(21(31)26-20-25-16-8-14(22)3-4-17(16)32-20)5-6-28(11)19-15(23)7-13(9-24-19)18(30)12(2)29/h3-4,7-9,11-12,18,29-30H,5-6,10H2,1-2H3,(H,25,26,31)/t11-,12-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	249	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair