BDBM211961 US9290482, 1

SMILES: COc1nccc2oc(cc12)-c1cnc2ccc(OC[C@H]3CNCCO3)nn12

InChI Key: InChIKey=OJBINZYFXHKYFD-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 211961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM211961 (US9290482, 1) Show SMILES COc1nccc2oc(cc12)-c1cnc2ccc(OC[C@H]3CNCCO3)nn12 |r| Show InChI InChI=1S/C19H19N5O4/c1-25-19-13-8-16(28-15(13)4-5-21-19)14-10-22-17-2-3-18(23-24(14)17)27-11-12-9-20-6-7-26-12/h2-5,8,10,12,20H,6-7,9,11H2,1H3/t12-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	22
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nl nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate ...				US Patent US9290482 (2016) BindingDB Entry DOI: 10.7270/Q2B856ZD
					More data for this Ligand-Target Pair