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SMILES: Cc1cc(C)c2cc(Cn3cc(cn3)C(=O)NCc3ccc(N)nc3C)c(C)nc2c1

InChI Key: InChIKey=LVJONVYRGYYEGZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212129   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasma kallikrein


(Homo sapiens (Human))		BDBM212129
PNG
(US9290485, 161)
Show SMILES Cc1cc(C)c2cc(Cn3cc(cn3)C(=O)NCc3ccc(N)nc3C)c(C)nc2c1
Show InChI InChI=1S/C24H26N6O/c1-14-7-15(2)21-9-19(17(4)28-22(21)8-14)12-30-13-20(11-27-30)24(31)26-10-18-5-6-23(25)29-16(18)3/h5-9,11,13H,10,12H2,1-4H3,(H2,25,29)(H,26,31)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/a7.825



NOVARTIS AG

US Patent


Assay Description
Enzymatic reactions were conducted in â¿¿assay bufferâ¿¿, comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For th...

US Patent US9290485 (2016)


BindingDB Entry DOI: 10.7270/Q26H4G73
More data for this
Ligand-Target Pair