BDBM212190 US9290487, compound of Ex. 38

SMILES: CSc1cc(F)c(F)cc1-c1ccc(OCc2cccc(c2)C(=O)N2CCC[C@H]2C(O)=O)cc1

InChI Key: InChIKey=ZLUJVXMVJGCMBU-QHCPKHFHSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase (GYS1) (Homo sapiens (Human))	BDBM212190 (US9290487, compound of Ex. 38) Show SMILES CSc1cc(F)c(F)cc1-c1ccc(OCc2cccc(c2)C(=O)N2CCC[C@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C26H23F2NO4S/c1-34-24-14-22(28)21(27)13-20(24)17-7-9-19(10-8-17)33-15-16-4-2-5-18(12-16)25(30)29-11-3-6-23(29)26(31)32/h2,4-5,7-10,12-14,23H,3,6,11,15H2,1H3,(H,31,32)/t23-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	29	n/a	n/a	7.3	30
AJINOMOTO CO., INC. US Patent					Assay Description To a polystyrene 96-well plate, a solution containing 30 mM glycylglycine (pH 7.3), 40 mM KCl, 20 mM MgCl2, 9.2% DMSO containing one of the test comp...				US Patent US9290487 (2016) BindingDB Entry DOI: 10.7270/Q22R3QGX
					More data for this Ligand-Target Pair