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SMILES: Cc1csc(NC(=O)c2cc(cn3ncnc23)-c2ccncc2)n1

InChI Key: InChIKey=WRQUJAFSKSEQGH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212378   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM212378
PNG
(US9550778, chem-us-00220)
Show SMILES Cc1csc(NC(=O)c2cc(cn3ncnc23)-c2ccncc2)n1
Show InChI InChI=1S/C16H12N6OS/c1-10-8-24-16(20-10)21-15(23)13-6-12(11-2-4-17-5-3-11)7-22-14(13)18-9-19-22/h2-9H,1H3,(H,20,21,23)
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PC cid
PC sid
UniChem
US Patent
n/an/a 8.07E+3n/an/an/an/a7.425



Vanderbilt University

US Patent


Assay Description
The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...

US Patent US9550778 (2017)


BindingDB Entry DOI: 10.7270/Q24M96J4
More data for this
Ligand-Target Pair