null

SMILES: CC(C)c1c(F)cncc1-c1cc(F)c-2c(CCc3nnc(C)n-23)c1

InChI Key: InChIKey=KGAFNYRYMCYLBY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM212443 (US9278093, 3) Show SMILES CC(C)c1c(F)cncc1-c1cc(F)c-2c(CCc3nnc(C)n-23)c1 Show InChI InChI=1S/C19H18F2N4/c1-10(2)18-14(8-22-9-16(18)21)13-6-12-4-5-17-24-23-11(3)25(17)19(12)15(20)7-13/h6-10H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.97E+3	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent					Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ...				US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM212443 (US9278093, 3) Show SMILES CC(C)c1c(F)cncc1-c1cc(F)c-2c(CCc3nnc(C)n-23)c1 Show InChI InChI=1S/C19H18F2N4/c1-10(2)18-14(8-22-9-16(18)21)13-6-12-4-5-17-24-23-11(3)25(17)19(12)15(20)7-13/h6-10H,4-5H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp.; ElexoPharm GmbH US Patent					Assay Description Compounds of the Examples 1 to 3 were assayed for V79-Human-CYP11B2 and V79-Human-CYP11B1 by modifying the protocol described in J. Steroid Biochem. ...				US Patent US9278093 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N5D
					More data for this Ligand-Target Pair