BDBM21254 1-(4-chlorophenyl)-N-[(3,4-dichlorophenyl)methyl]-3-methyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide::Pyrazole-4-carboxamide analogue, 21

SMILES: Cc1nn(c(c1C(=O)NCc1ccc(Cl)c(Cl)c1)-n1cccc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=FSDRQNSFQHSTFS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21254 (1-(4-chlorophenyl)-N-[(3,4-dichlorophenyl)methyl]-...) Show SMILES Cc1nn(c(c1C(=O)NCc1ccc(Cl)c(Cl)c1)-n1cccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17Cl3N4O/c1-14-20(21(30)26-13-15-4-9-18(24)19(25)12-15)22(28-10-2-3-11-28)29(27-14)17-7-5-16(23)6-8-17/h2-12H,13H2,1H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.82E+3	-7.69	n/a	n/a	n/a	n/a	n/a	7.4	30
Sapienza Universitàadi Roma					Assay Description IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...				J Med Chem 51: 1560-76 (2008) Article DOI: 10.1021/jm070566z BindingDB Entry DOI: 10.7270/Q2GX48V9
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM21254 (1-(4-chlorophenyl)-N-[(3,4-dichlorophenyl)methyl]-...) Show SMILES Cc1nn(c(c1C(=O)NCc1ccc(Cl)c(Cl)c1)-n1cccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17Cl3N4O/c1-14-20(21(30)26-13-15-4-9-18(24)19(25)12-15)22(28-10-2-3-11-28)29(27-14)17-7-5-16(23)6-8-17/h2-12H,13H2,1H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universitàadi Roma					Assay Description IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...				J Med Chem 51: 1560-76 (2008) Article DOI: 10.1021/jm070566z BindingDB Entry DOI: 10.7270/Q2GX48V9
					More data for this Ligand-Target Pair