BDBM212937 US9278960, 4-22-A::US9278960, 4-22-B
SMILES: C[C@H]1CNC(CN1Cc1ccc2c(cc(nc2c1)C(N)=O)-c1ccc(F)cc1)C(F)(F)F
InChI Key: InChIKey=WEPMFGFQUDQCQI-JRTLGTJJSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
mGluR2 and G alpha 16 (Homo sapiens (Human)) | BDBM212937 (US9278960, 4-22-A | US9278960, 4-22-B) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR... | US Patent US9278960 (2016) BindingDB Entry DOI: 10.7270/Q2MK6BQW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
mGluR2 and G alpha 16 (Homo sapiens (Human)) | BDBM212937 (US9278960, 4-22-A | US9278960, 4-22-B) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR... | US Patent US9278960 (2016) BindingDB Entry DOI: 10.7270/Q2MK6BQW | |||||||||||
More data for this Ligand-Target Pair |