BDBM213201 US9290517, 131
SMILES: Cc1cc(-c2ccc(cc2)-c2ccc(cc2)-c2nc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)c(=O)[nH]n1
InChI Key: InChIKey=AEVQBBDRFREYSM-CWNOGFBWSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMPK alpha2/beta1/gamma1 (Homo sapiens (Human)) | BDBM213201 (US9290517, 131) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3 | n/a | n/a | 7.3 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat... | US Patent US9290517 (2016) BindingDB Entry DOI: 10.7270/Q2C24V7Q | |||||||||||
More data for this Ligand-Target Pair |