BDBM21341 2-[1-(benzenesulfonyl)-1H-indol-3-yl]ethan-1-amine::CHEMBL363275::N1-Phenylsulfonyltryptamine, 11a
SMILES: NCCc1cn(c2ccccc12)S(=O)(=O)c1ccccc1
InChI Key: InChIKey=GSOZASAZEKGFMK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM21341 (2-[1-(benzenesulfonyl)-1H-indol-3-yl]ethan-1-amine...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | -10.8 | n/a | n/a | 73 | n/a | n/a | 7.4 | 22 |
Wyeth Research | Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti... | J Med Chem 50: 5535-8 (2007) Article DOI: 10.1021/jm070521y BindingDB Entry DOI: 10.7270/Q23R0R5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM21341 (2-[1-(benzenesulfonyl)-1H-indol-3-yl]ethan-1-amine...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells | Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X | |||||||||||
More data for this Ligand-Target Pair |