BDBM21357 5-thiazolylsulfonyl tryptamine, 11p::5-{[3-(2-aminoethyl)-1H-indole-1-]sulfonyl}-4-methyl-1,3-thiazol-2-amine

SMILES: Cc1nc(N)sc1S(=O)(=O)n1cc(CCN)c2ccccc12

InChI Key: InChIKey=RKTUJGHCTYYOGY-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21357 (5-thiazolylsulfonyl tryptamine, 11p | 5-{[3-(2-ami...) Show SMILES Cc1nc(N)sc1S(=O)(=O)n1cc(CCN)c2ccccc12 Show InChI InChI=1S/C14H16N4O2S2/c1-9-13(21-14(16)17-9)22(19,20)18-8-10(6-7-15)11-4-2-3-5-12(11)18/h2-5,8H,6-7,15H2,1H3,(H2,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10	-10.8	n/a	n/a	9.60	n/a	n/a	7.4	22
Wyeth Research					Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...				J Med Chem 50: 5535-8 (2007) Article DOI: 10.1021/jm070521y BindingDB Entry DOI: 10.7270/Q23R0R5G
					More data for this Ligand-Target Pair