BDBM21455 3-({1-[(benzyloxy)carbonyl]pyrrolidin-2-yl}(hydroxy)phosphoryl)-2-methylpropanoic acid::Phosphinic Peptide Inhibitor, 14

SMILES: CC(CP(O)(O)C1=CCCN1C(=O)OCc1ccccc1)C(O)=O

InChI Key: InChIKey=AARIUGSBSPVDBN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme 2 (Homo sapiens (Human))	BDBM21455 (3-({1-[(benzyloxy)carbonyl]pyrrolidin-2-yl}(hydrox...) Show SMILES CC(CP(O)(O)C1=CCCN1C(=O)OCc1ccccc1)C(O)=O |t:6| Show InChI InChI=1S/C16H22NO6P/c1-12(15(18)19)11-24(21,22)14-8-5-9-17(14)16(20)23-10-13-6-3-2-4-7-13/h2-4,6-8,12,21-22,24H,5,9-11H2,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	-7.53	n/a	n/a	n/a	n/a	n/a	6.8	25
University of Athens					Assay Description Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...				J Med Chem 51: 2216-2226 (2008) Article DOI: 10.1021/jm701275z BindingDB Entry DOI: 10.7270/Q2QF8R4J
					More data for this Ligand-Target Pair