BDBM21460 3-[(1-amino-2-phenylethyl)(hydroxy)phosphoryl]-2-benzylpropanoic acid::CHEMBL34068::Phosphinic Peptide Inhibitor, 19

SMILES: OC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1

InChI Key: InChIKey=ADPMNGVGXYXGMF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM21460 (3-[(1-amino-2-phenylethyl)(hydroxy)phosphoryl]-2-b...) Show SMILES OC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1 Show InChI InChI=1S/C18H22NO4P/c19-17(12-15-9-5-2-6-10-15)24(22,23)13-16(18(20)21)11-14-7-3-1-4-8-14/h1-10,16,19,22-24H,11-13H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of pig kidney Aminopeptidase N				Bioorg Med Chem Lett 9: 1511-6 (1999) BindingDB Entry DOI: 10.7270/Q2H132JR
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme 2 (Homo sapiens (Human))	BDBM21460 (3-[(1-amino-2-phenylethyl)(hydroxy)phosphoryl]-2-b...) Show SMILES OC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1 Show InChI InChI=1S/C18H22NO4P/c19-17(12-15-9-5-2-6-10-15)24(22,23)13-16(18(20)21)11-14-7-3-1-4-8-14/h1-10,16,19,22-24H,11-13H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	>-6.82	n/a	n/a	n/a	n/a	n/a	6.8	25
University of Athens					Assay Description Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...				J Med Chem 51: 2216-2226 (2008) Article DOI: 10.1021/jm701275z BindingDB Entry DOI: 10.7270/Q2QF8R4J
					More data for this Ligand-Target Pair