BDBM21461 3-[(1-amino-3-methylbutyl)(hydroxy)phosphoryl]-2-benzylpropanoic acid::CHEMBL36716::Phosphinic Peptide Inhibitor, 20
SMILES: CC(C)CC(=N)P(O)(O)CC(Cc1ccccc1)C(O)=O
InChI Key: InChIKey=PUCLBXYCGPUOHC-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aminopeptidase N (Sus scrofa (Pig)) | BDBM21461 (3-[(1-amino-3-methylbutyl)(hydroxy)phosphoryl]-2-b...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibition of pig kidney Aminopeptidase N | Bioorg Med Chem Lett 9: 1511-6 (1999) BindingDB Entry DOI: 10.7270/Q2H132JR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme 2 (Homo sapiens (Human)) | BDBM21461 (3-[(1-amino-3-methylbutyl)(hydroxy)phosphoryl]-2-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | >-6.82 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
University of Athens | Assay Description Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra... | J Med Chem 51: 2216-2226 (2008) Article DOI: 10.1021/jm701275z BindingDB Entry DOI: 10.7270/Q2QF8R4J | |||||||||||
More data for this Ligand-Target Pair |