BDBM214693 US9296703, 1

SMILES: Oc1cc(Nc2ncc(Cl)c(n2)-c2cccc(NC(=O)C=C)c2)ccc1N1CCOCC1

InChI Key: InChIKey=QLQDJIYCXRRPQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM214693 (US9296703, 1) Show SMILES Oc1cc(Nc2ncc(Cl)c(n2)-c2cccc(NC(=O)C=C)c2)ccc1N1CCOCC1 Show InChI InChI=1S/C23H22ClN5O3/c1-2-21(31)26-16-5-3-4-15(12-16)22-18(24)14-25-23(28-22)27-17-6-7-19(20(30)13-17)29-8-10-32-11-9-29/h2-7,12-14,30H,1,8-11H2,(H,26,31)(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...				US Patent US9296703 (2016) BindingDB Entry DOI: 10.7270/Q2Q81BW2
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