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SMILES: [O-]C(=O)CCCN1C(=S)S\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O

InChI Key: InChIKey=VZDIEMVRQWTFKY-GDNBJRDFSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214752   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microtubule-associated protein


(Homo sapiens (Human))		BDBM214752
PNG
(Rhodanines, 40A)
Show SMILES [O-]C(=O)CCCN1C(=S)S\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O
Show InChI InChI=1S/C18H14ClNO4S2/c19-12-4-1-3-11(9-12)14-7-6-13(24-14)10-15-17(23)20(18(25)26-15)8-2-5-16(21)22/h1,3-4,6-7,9-10H,2,5,8H2,(H,21,22)/p-1/b15-10-
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.22E+3n/an/an/an/a7.4n/a



The Ohio State University



Assay Description
The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...

J Biol Chem 288: 32599-611 (2013)


Article DOI: 10.1074/jbc.M113.503474
BindingDB Entry DOI: 10.7270/Q2R49PMK
More data for this
Ligand-Target Pair