BDBM214758 Rhodanines, 46A

SMILES: [O-]C(=O)CN1C(=S)O\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O

InChI Key: InChIKey=QHYLVKDNWBBXSU-QPEQYQDCSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM214758 (Rhodanines, 46A) Show SMILES [O-]C(=O)CN1C(=S)O\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O Show InChI InChI=1S/C16H10ClNO5S/c17-10-3-1-2-9(6-10)12-5-4-11(22-12)7-13-15(21)18(8-14(19)20)16(24)23-13/h1-7H,8H2,(H,19,20)/p-1/b13-7-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair