BDBM215733 US9296748, II-20

SMILES: Cc1cc(cn(C)c1=O)-c1nc2cnc(cc2n1Cc1cccnc1)N1CCOCC1

InChI Key: InChIKey=KGVQTABWENXBRK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 215733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (BRD4) (aa 44-168) (Homo sapiens (Human))	BDBM215733 (US9296748, II-20) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2cnc(cc2n1Cc1cccnc1)N1CCOCC1 Show InChI InChI=1S/C23H24N6O2/c1-16-10-18(15-27(2)23(16)30)22-26-19-13-25-21(28-6-8-31-9-7-28)11-20(19)29(22)14-17-4-3-5-24-12-17/h3-5,10-13,15H,6-9,14H2,1-2H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...				US Patent US9296748 (2016) BindingDB Entry DOI: 10.7270/Q21G0K4K
					More data for this Ligand-Target Pair