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BDBM21701 2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]pyrrolidin-3-yl}-1H-1,3-benzodiazole::benzimidazole, (rac) 10::racemic mixture

SMILES: CCc1nc2ccccc2n1C1CCN(C1)C(=O)c1cc2cc(OC)ccc2[nH]1

InChI Key: InChIKey=QVEGWYOUJZKXIV-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21701   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM21701
PNG
(2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]py...)
Show SMILES CCc1nc2ccccc2n1C1CCN(C1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C23H24N4O2/c1-3-22-25-19-6-4-5-7-21(19)27(22)16-10-11-26(14-16)23(28)20-13-15-12-17(29-2)8-9-18(15)24-20/h4-9,12-13,16,24H,3,10-11,14H2,1-2H3
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 130n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair