BDBM217353 Isoflurane

SMILES: FC(F)OC(Cl)C(F)(F)F

InChI Key: InChIKey=PIWKPBJCKXDKJR-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 217353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α7β2 nAChR (Homo sapiens (Human))	BDBM217353 (Isoflurane) Show SMILES FC(F)OC(Cl)C(F)(F)F Show InChI InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	25
University of Pittsburgh School of Medicine					Assay Description Functional measurements were performed using perforated patch whole cell recordings coupled with a two-barrel drug application system [Liu et al., J....				J Biol Chem 288: 35793-800 (2013) Article DOI: 10.1074/jbc.M113.508333 BindingDB Entry DOI: 10.7270/Q24748QH
					More data for this Ligand-Target Pair