BDBM217358 α2,3'-sialyllactose::3-SL
SMILES: CC(=O)NC1C(O)CC(OC2C(O)C(CO)OC(OC3C(CO)OC(O)C(O)C3O)C2O)(OC1[C@H](O)[C@H](O)CO)C(O)=O
InChI Key: InChIKey=CILYIEBUXJIHCO-PIAFIIEKSA-N
Data: 2 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
trans-Sialidase (TS D247A) (Trypanosoma cruzi) | BDBM217358 (α2,3'-sialyllactose | 3-SL) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.07E+5 | n/a | n/a | n/a | n/a | 11 |
Universidade Federal do Rio de Janeiro | Assay Description Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0... | J Biol Chem 289: 423-36 (2014) Article DOI: 10.1074/jbc.M112.399303 BindingDB Entry DOI: 10.7270/Q2VT1QZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
trans-Sialidase (TS Y342H) (Trypanosoma cruzi) | BDBM217358 (α2,3'-sialyllactose | 3-SL) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.34E+5 | n/a | n/a | n/a | n/a | 11 |
Universidade Federal do Rio de Janeiro | Assay Description Solutions of TS, TSY342H, and TSD247A in 20 mM Tris-HCl were exchanged with deuterated PBS using four cycles of concentration with Amicon Ultra (50,0... | J Biol Chem 289: 423-36 (2014) Article DOI: 10.1074/jbc.M112.399303 BindingDB Entry DOI: 10.7270/Q2VT1QZ8 | |||||||||||
More data for this Ligand-Target Pair |