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SMILES: CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O

InChI Key: InChIKey=SPPARUSJHLYZPL-CWRASOKGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 217377   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein phosphatase 5


(Homo sapiens (Human))		BDBM217377
PNG
(GSGPTMEEVD)
Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r|
Show InChI InChI=1S/C40H64N10O19S/c1-18(2)31(38(66)47-23(40(68)69)14-30(59)60)48-36(64)21(8-10-29(57)58)45-34(62)20(7-9-28(55)56)44-35(63)22(11-13-70-4)46-39(67)32(19(3)52)49-37(65)25-6-5-12-50(25)27(54)16-42-33(61)24(17-51)43-26(53)15-41/h18-25,31-32,51-52H,5-17,41H2,1-4H3,(H,42,61)(H,43,53)(H,44,63)(H,45,62)(H,46,67)(H,47,66)(H,48,64)(H,49,65)(H,55,56)(H,57,58)(H,59,60)(H,68,69)/t19-,20+,21+,22+,23+,24+,25+,31+,32+/m1/s1
PDB

UniProtKB/SwissProt

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KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 133n/an/an/a7.425



University of Michigan



Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl...

J Biol Chem 289: 2908-17 (2014)


Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN
More data for this
Ligand-Target Pair