BDBM217388 Steroid scaffold, 13
SMILES: C[C@@]12CCC[C@H]1[C@@H]1CC[C@H]3CC(=O)[C@H](Br)C[C@]3(C)[C@H]1CC2
InChI Key: InChIKey=WDTWEWZLXQZFPG-DBQFFBIKSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ghrelin O-acyltransferase (Homo sapiens (Human)) | BDBM217388 (Steroid scaffold, 13) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >4.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Syracuse University | Assay Description Assays were performed with ~100 μg of membrane protein, as determined by a Bradford assay. The membrane fraction was preincubated with 1 μM met... | Biochemistry 56: 919-931 (2017) Article DOI: 10.1021/acs.biochem.6b01008 BindingDB Entry DOI: 10.7270/Q270808D | |||||||||||
More data for this Ligand-Target Pair |