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SMILES: ONC(=O)c1ccc(Cn2cccc2)cc1

InChI Key: InChIKey=UINKJJGYTJDCMY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM218200 (US9249087, 41) Show SMILES ONC(=O)c1ccc(Cn2cccc2)cc1 Show InChI InChI=1S/C12H12N2O2/c15-12(13-16)11-5-3-10(4-6-11)9-14-7-1-2-8-14/h1-8,16H,9H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.3	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM218200 (US9249087, 41) Show SMILES ONC(=O)c1ccc(Cn2cccc2)cc1 Show InChI InChI=1S/C12H12N2O2/c15-12(13-16)11-5-3-10(4-6-11)9-14-7-1-2-8-14/h1-8,16H,9H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.73E+3	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair