BDBM218206 US9249087, 47

SMILES: CN(C)c1ccc(Cc2ccc(cc2)C(=O)NO)cc1

InChI Key: InChIKey=MNOOUMMGNAQTKF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM218206 (US9249087, 47) Show SMILES CN(C)c1ccc(Cc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C16H18N2O2/c1-18(2)15-9-5-13(6-10-15)11-12-3-7-14(8-4-12)16(19)17-20/h3-10,20H,11H2,1-2H3,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.9	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM218206 (US9249087, 47) Show SMILES CN(C)c1ccc(Cc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C16H18N2O2/c1-18(2)15-9-5-13(6-10-15)11-12-3-7-14(8-4-12)16(19)17-20/h3-10,20H,11H2,1-2H3,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.87E+3	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair