null

SMILES: CN1CCN(CCc2cc(-c3ccc(cc3)C(=O)NO)c3ccccc23)CC1

InChI Key: InChIKey=WJENSOCZZVSPGH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM218230 (US9249087, Table 1 , Compound 7) Show SMILES CN1CCN(CCc2cc(-c3ccc(cc3)C(=O)NO)c3ccccc23)CC1 Show InChI InChI=1S/C23H26N3O2/c1-25-12-14-26(15-13-25)11-10-19-16-22(21-5-3-2-4-20(19)21)17-6-8-18(9-7-17)23(27)24-28/h2-9,16,28H,10-15H2,1H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM218230 (US9249087, Table 1 , Compound 7) Show SMILES CN1CCN(CCc2cc(-c3ccc(cc3)C(=O)NO)c3ccccc23)CC1 Show InChI InChI=1S/C23H26N3O2/c1-25-12-14-26(15-13-25)11-10-19-16-22(21-5-3-2-4-20(19)21)17-6-8-18(9-7-17)23(27)24-28/h2-9,16,28H,10-15H2,1H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	174	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM218230 (US9249087, Table 1 , Compound 7) Show SMILES CN1CCN(CCc2cc(-c3ccc(cc3)C(=O)NO)c3ccccc23)CC1 Show InChI InChI=1S/C23H26N3O2/c1-25-12-14-26(15-13-25)11-10-19-16-22(21-5-3-2-4-20(19)21)17-6-8-18(9-7-17)23(27)24-28/h2-9,16,28H,10-15H2,1H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.94	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair