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SMILES: COC[C@@H]1CCCC1c1ccc(cc1)C(=O)NO

InChI Key: InChIKey=FSLVYYNKYSIGHI-UEWDXFNNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM218239 (US9249087, Table 1 , Compound 16) Show SMILES COC[C@@H]1CCCC1c1ccc(cc1)C(=O)NO |r| Show InChI InChI=1S/C14H19NO3/c1-18-9-12-3-2-4-13(12)10-5-7-11(8-6-10)14(16)15-17/h5-8,12-13,17H,2-4,9H2,1H3,(H,15,16)/t12-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.79E+4	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM218239 (US9249087, Table 1 , Compound 16) Show SMILES COC[C@@H]1CCCC1c1ccc(cc1)C(=O)NO |r| Show InChI InChI=1S/C14H19NO3/c1-18-9-12-3-2-4-13(12)10-5-7-11(8-6-10)14(16)15-17/h5-8,12-13,17H,2-4,9H2,1H3,(H,15,16)/t12-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM218239 (US9249087, Table 1 , Compound 16) Show SMILES COC[C@@H]1CCCC1c1ccc(cc1)C(=O)NO |r| Show InChI InChI=1S/C14H19NO3/c1-18-9-12-3-2-4-13(12)10-5-7-11(8-6-10)14(16)15-17/h5-8,12-13,17H,2-4,9H2,1H3,(H,15,16)/t12-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair