null

SMILES: CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1c(F)cccc1F

InChI Key: InChIKey=CXJXEBLPEHWJRS-KBXCAEBGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218279 (US9284333, 16t | US9884860, Example 16t) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1c(F)cccc1F |r| Show InChI InChI=1S/C23H27F2N3O3/c1-3-18(21-16(24)7-4-8-17(21)25)26-22(29)15-12-19(28-10-11-31-13-20(15)28)23(30)27-9-5-6-14(27)2/h4,7-8,12,14,18H,3,5-6,9-11,13H2,1-2H3,(H,26,29)/t14-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9884860 (2018) BindingDB Entry DOI: 10.7270/Q2862JGT
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218279 (US9284333, 16t | US9884860, Example 16t) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1c(F)cccc1F |r| Show InChI InChI=1S/C23H27F2N3O3/c1-3-18(21-16(24)7-4-8-17(21)25)26-22(29)15-12-19(28-10-11-31-13-20(15)28)23(30)27-9-5-6-14(27)2/h4,7-8,12,14,18H,3,5-6,9-11,13H2,1-2H3,(H,26,29)/t14-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9284333 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FMC
					More data for this Ligand-Target Pair