null

SMILES: CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1c(F)cc(cc1F)C(F)(F)F

InChI Key: InChIKey=ZGPNNTSNYGLHHT-SCLBCKFNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218346 (US9284333, 16cl | US9884860, Example 16cl) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1c(F)cc(cc1F)C(F)(F)F |r| Show InChI InChI=1S/C24H26F5N3O3/c1-3-18(21-16(25)9-14(10-17(21)26)24(27,28)29)30-22(33)15-11-19(32-7-8-35-12-20(15)32)23(34)31-6-4-5-13(31)2/h9-11,13,18H,3-8,12H2,1-2H3,(H,30,33)/t13-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9884860 (2018) BindingDB Entry DOI: 10.7270/Q2862JGT
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218346 (US9284333, 16cl | US9884860, Example 16cl) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2CCOCc12)c1c(F)cc(cc1F)C(F)(F)F |r| Show InChI InChI=1S/C24H26F5N3O3/c1-3-18(21-16(25)9-14(10-17(21)26)24(27,28)29)30-22(33)15-11-19(32-7-8-35-12-20(15)32)23(34)31-6-4-5-13(31)2/h9-11,13,18H,3-8,12H2,1-2H3,(H,30,33)/t13-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9284333 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FMC
					More data for this Ligand-Target Pair