null

SMILES: CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2CCOCc12)c1ccc(cn1)C(F)(F)F

InChI Key: InChIKey=TXPAJCIIMTVMEF-FOIQADDNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218388 (US9284333, 16eg | US9884860, Example 16eg) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2CCOCc12)c1ccc(cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H26F4N4O3/c1-3-20(21-9-6-17(13-31-21)26(28,29)30)33-24(35)19-12-22(34-10-11-37-14-23(19)34)25(36)32-15(2)16-4-7-18(27)8-5-16/h4-9,12-13,15,20H,3,10-11,14H2,1-2H3,(H,32,36)(H,33,35)/t15-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9884860 (2018) BindingDB Entry DOI: 10.7270/Q2862JGT
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218388 (US9284333, 16eg | US9884860, Example 16eg) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)n2CCOCc12)c1ccc(cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H26F4N4O3/c1-3-20(21-9-6-17(13-31-21)26(28,29)30)33-24(35)19-12-22(34-10-11-37-14-23(19)34)25(36)32-15(2)16-4-7-18(27)8-5-16/h4-9,12-13,15,20H,3,10-11,14H2,1-2H3,(H,32,36)(H,33,35)/t15-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9284333 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FMC
					More data for this Ligand-Target Pair