null

SMILES: CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccc(CC(=O)OC)cc2)n2CCOCc12)c1ccccc1

InChI Key: InChIKey=VRLADZZCLMUROT-HSZRJFAPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218483 (US9284333, 16is | US9884860, Example 16is) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccc(CC(=O)OC)cc2)n2CCOCc12)c1ccccc1 |r| Show InChI InChI=1S/C28H31N3O5/c1-3-23(21-7-5-4-6-8-21)30-27(33)22-16-24(31-13-14-36-18-25(22)31)28(34)29-17-20-11-9-19(10-12-20)15-26(32)35-2/h4-12,16,23H,3,13-15,17-18H2,1-2H3,(H,29,34)(H,30,33)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9884860 (2018) BindingDB Entry DOI: 10.7270/Q2862JGT
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218483 (US9284333, 16is | US9884860, Example 16is) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)NCc2ccc(CC(=O)OC)cc2)n2CCOCc12)c1ccccc1 |r| Show InChI InChI=1S/C28H31N3O5/c1-3-23(21-7-5-4-6-8-21)30-27(33)22-16-24(31-13-14-36-18-25(22)31)28(34)29-17-20-11-9-19(10-12-20)15-26(32)35-2/h4-12,16,23H,3,13-15,17-18H2,1-2H3,(H,29,34)(H,30,33)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9284333 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FMC
					More data for this Ligand-Target Pair